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[Study on the recombinant expression of Hantaan virus protein N and the establishment and application of rNP-IgM direct capture ELISA].

Authors
  • Zhu, Han-Ping1
  • Yao, Ping-Ping
  • Xu, Fang
  • Weng, Jing-Qing
  • Xie, Rong-Hui
  • Lu, Qun-Ying
  • Zhu, Zhi-Yong
  • Yan, Jie
  • 1 Department of Medical Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China. , (China)
Type
Published Article
Journal
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Publication Date
Jul 01, 2007
Volume
28
Issue
7
Pages
692–696
Identifiers
PMID: 18069562
Source
Medline
License
Unknown

Abstract

We successfully constructed a high efficient prokaryotic expression system of NP encoding gene of hantavirus strain HV-Z10. The rNP-IgM direct capture ELISA that established in this study could be used as a new serological test for HFRS diagnosis because of its simplicity, safety, with high sensitivity and specificity.

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