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A Study on the Expression of BCR-ABL Transcript in Mixed Phenotype Acute Leukemia (MPAL) Cases Using the Reverse Transcriptase Polymerase Reaction Assay (RT-PCR) and its Correlation with Hematological Remission Status Post Initial Induction Therapy.

Authors
  • Bhatia, Prateek
  • Binota, Jogeshwar
  • Varma, Neelam
  • Bansal, Deepak
  • Trehan, Amita
  • Marwaha, Ram Kumar
  • Malhotra, Pankaj
  • Varma, Subhash
Type
Published Article
Journal
Mediterranean Journal of Hematology and Infectious Diseases
Publisher
"Institute of Hematology, Catholic University"
Publication Date
Jan 01, 2012
Volume
4
Issue
1
Identifiers
DOI: 10.4084/MJHID.2012.024
PMID: 22708039
Source
Medline
License
Unknown

Abstract

All the 4 positive MPAL cases presented with high TLC and low platelet count (p<0.05). The positive cases also showed hematological remission at post induction check marrow (blasts<5%). This could partly be explained due to good response to the imatinib added to the treatment protocol.

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