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The study of efficacy of lamivudine in patients with severe acute hepatitis B.

Authors
  • Yu, Jian-Wu
  • Sun, Li-Jie
  • Zhao, Yong-Hua
  • Kang, Peng
  • Li, Shu-Chen
Type
Published Article
Journal
Digestive Diseases and Sciences
Publisher
Springer-Verlag
Publication Date
Mar 01, 2010
Volume
55
Issue
3
Pages
775–783
Identifiers
DOI: 10.1007/s10620-009-1060-5
PMID: 19957031
Source
Medline
License
Unknown

Abstract

Early treatment with lamivudine leads to a greater decrease in HBV DNA level, better clinical improvement and mortality improvement in patients with severe acute hepatitis B, but with a lower seroconversion rate. A rapid decline of HBV DNA load is a good predictor for the treatment outcome.

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