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Studies on acquired immunity to coccidiosis in bursaless and thymectomized fowls

Authors
  • A. E. Pierce
  • P. L. Long
Publication Date
Nov 01, 1965
Source
PMC
Keywords
License
Unknown

Abstract

Fowls hatched from embryos inoculated in ovo with testosterone between the sixth and ninth day of incubation hatched without a detectable bursa of Fabricius. These fowls failed to develop antibodies as the result of repeated infection with Eimeria tenella and levels of serum immune globulin were usually markedly reduced or undetectable. There were very few pyroninophilic cells in the caeca or spleen and secondary foci in the spleen and caecal lymphoid tissue were either not detected or were very reduced in number. The spleen and thymus weights were significantly reduced by testosterone treatment.

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