Affordable Access

Studies on influenza infection in ferrets by means of fluorescein-labelled antibody. II. The role of soluble antigen in nuclear fluorescence and cross-reactions.

Authors
Type
Published Article
Journal
The Journal of experimental medicine
Publication Date
Volume
101
Issue
6
Pages
677–686
Identifiers
PMID: 14367688
Source
Medline
Keywords
  • Antigens And Antibodies
  • Influenza/Experimental

Abstract

Yellow-green fluorescence representing viral antigens was detected in both the nucleus and cytoplasm of epithelial cells of the respiratory tract in ferrets infected with influenza virus. This nuclear fluorescence was the chief manifestation of cross-fluorescent staining reactions among three strains of influenza A virus studied, PR8, Farrington, and Fm(1). Absorption experiments with influenza viral V and soluble S antigens showed that S antigen was responsible for the presence of fluorescence in the nucleus and for the cross-staining reactions among these strains.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments