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Studies on cytochrome c. XIV. Synthesis of the protected heptadecapeptide (sequence 88-104) of horse heart cytochrome c.

Authors
  • Borin, G
  • Filippi, B
  • Cavaggion, F
  • Marchiori, F
Type
Published Article
Journal
International journal of peptide & protein research
Publisher
Wiley (Blackwell Publishing)
Publication Date
Jan 01, 1977
Volume
10
Issue
2
Pages
95–101
Identifiers
PMID: 197036
Source
Medline
License
Unknown

Abstract

A solution synthesis is described of the partially protected N alpha-benzyloxycarbonylheptadecapeptide Z-Lys (Tfa)-Thr-Glu-Arg-Glu-Asp-Leu-Ile-Ala-Tyr-Leu-Lys (Tfa)-Lys (Tfa)-Ala-Thr-Asn-Glu (OBu t)-OBu t corresponding to sequence 88-104 of horse heart cytochrome c. The synthesis is achieved through the preparation of two subunits H1 (sequence 88-96) and H2 (sequence 97-104) and their linkage by an azide coupling step.

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