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ST-Segment Elevation Myocardial Infarction Related to Potential Spontaneous Coronary Thrombosis in Pheochromocytoma Crisis

Authors
  • Chen, Fei
  • Zheng, Mingxia
  • Li, Xi
  • Peng, Yong
  • Chen, Mao
Type
Published Article
Journal
Frontiers in Endocrinology
Publisher
Frontiers Media SA
Publication Date
Mar 18, 2020
Volume
11
Identifiers
DOI: 10.3389/fendo.2020.00140
PMID: 32256452
PMCID: PMC7093383
Source
PubMed Central
Keywords
License
Unknown

Abstract

Pheochromocytoma crisis is a rare and possibly fatal emergency. Hypersecreted catecholamines may result in myocardial injury via its direct toxic effect on cardiomyocytes or mediating vasoconstriction which will reduce coronary blood flow in this special setting. Interestingly, several case studies have reported the occurrence of ST-segment elevation myocardial infarction in patients with pheochromocytoma crisis. However, no one found the angiographic evidence of occlusive thrombus in the infarct-related coronary artery. Additionally, pheochromocytoma can induce hypercoagulability and promote thrombosis, but spontaneous coronary thrombosis has never been reported in this condition. Here, we report an unusual case of pheochromocytoma crisis presenting with STEMI due to spontaneous coronary thrombosis.

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