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Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents.

Authors
  • Balakrishnan, Brinda
  • Tzafriri, Abraham R
  • Seifert, Philip
  • Groothuis, Adam
  • Rogers, Campbell
  • Edelman, Elazer R
Type
Published Article
Journal
Circulation
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jun 07, 2005
Volume
111
Issue
22
Pages
2958–2965
Identifiers
PMID: 15927969
Source
Medline
License
Unknown

Abstract

Simulations that coupled strut configurations with flow dynamics correlated with in vivo effects and revealed that drug deposition occurs less via contact between drug coating and the arterial wall than via flow-mediated deposition of blood-solubilized drug.

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