Structures of prokaryotic ribosomal proteins: implications for RNA binding and evolution.
- Authors
- Type
- Published Article
- Journal
- Biochemistry and cell biology = Biochimie et biologie cellulaire
- Publication Date
- Jan 01, 1995
- Volume
- 73
- Issue
- 11-12
- Pages
- 979–986
- Identifiers
- PMID: 8722013
- Source
- Medline
- License
- Unknown
Abstract
After a long hiatus, the pace of determination of the structures of ribosomal proteins has accelerated dramatically. We discuss here the structures of five ribosomal proteins from Bacillus stearothermophilus: S5, S17, L6, L9, and L14. These structures represent several new motifs. Each of these structures has revealed new insights, and we have developed criteria for recognizing RNA-binding regions of each protein and correlating the structures with such properties as antibiotic resistance. The information here should also prove invaluable in an eventual high-resolution picture of the intact ribosome.