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THE STRUCTURE OF MYCOBACTIN P, A GROWTH FACTOR FOR MYCOBACTERIUM JOHNEI, AND THE SIGNIFICANCE OF ITS IRON COMPLEX.

Authors
  • SNOW, G A
Type
Published Article
Journal
The Biochemical journal
Publication Date
Jan 01, 1965
Volume
94
Pages
160–165
Identifiers
PMID: 14342223
Source
Medline
Keywords
License
Unknown

Abstract

1. The growth factor from Mycobacterium phlei is now named mycobactin P to distinguish it from related but chemically distinct growth factors from other species of mycobacteria. It is shown to comprise four closely similar chemical entities differing only in the fatty side chain. 2. The structure of the main component (85%) of mycobactin P has been established and the absolute configuration of all asymmetric centres determined. 3. Ferric mycobactin P has been crystallized; its structure is discussed. 4. Evidence is given for regarding ferric mycobactin P as a member of the class of compounds known as sideramines, though the mycobactins are more specialized than other sideramines.

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