Affordable Access

Structure and growth activities of the mandibular condyle in monkeys (Macaca fascicularis): II. Synergistic behavior of cell dynamics and metabolism.

Authors
  • Luder, H U
Type
Published Article
Journal
The American journal of anatomy
Publication Date
Feb 01, 1987
Volume
178
Issue
2
Pages
185–192
Identifiers
PMID: 3578082
Source
Medline
License
Unknown

Abstract

The mandibular condyles of eight growing male monkeys (Macaca fascicularis) were analyzed by using a combination of radioautographic and morphometric techniques. This was done with the aim of examining the dynamics in the structure and growth activities of the articular tissue covering as well as of the subchondral zone of erosion. The animals received 1 mCi/kg body weight 3H-proline 24 hr and 0.5 mCi/kg body weight 3H-thymidine 3 hr prior to death. Their age was estimated on the basis of skeletal maturation as recorded from radiographs of the hand and wrist. Consistently, the proliferative activity in the intermediate layer, the rates of cell turnover and growth of chondroblasts and chondrocytes, the rates of extracellular matrix production in the intermediate and chondral layers, as well as the resorptive and appositional activities in the zone of erosion were characterized by an in-concert behavior. This behavior suggests a general synergistic control of the various cell dynamic and metabolic processes affecting the rate of normal condylar growth.

Report this publication

Statistics

Seen <100 times