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Strict blood-pressure control and progression of renal failure in children.

Authors
  • And 16 more
Type
Published Article
Journal
New England Journal of Medicine
1533-4406
Publisher
New England Journal of Medicine
Publication Date
Volume
361
Issue
17
Pages
1639–1650
Identifiers
DOI: 10.1056/NEJMoa0902066
PMID: 19846849
Source
Medline
License
Unknown

Abstract

Intensified blood-pressure control, with target 24-hour blood-pressure levels in the low range of normal, confers a substantial benefit with respect to renal function among children with chronic kidney disease. Reappearance of proteinuria after initial successful pharmacologic blood-pressure control is common among children who are receiving long-term ACE inhibition. (ClinicalTrials.gov number, NCT00221845.)

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