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[Stress ulcer prophylaxis in the intensive care unit].

Authors
  • de Fijter, C W
  • Strack van Schijndel, R J
  • Thijs, L G
Type
Published Article
Journal
Nederlands tijdschrift voor geneeskunde
Publication Date
Dec 11, 1999
Volume
143
Issue
50
Pages
2519–2523
Identifiers
PMID: 10627754
Source
Medline
License
Unknown

Abstract

In the early years of intensive care a stress ulcer related bleeding, occurring in 20-30% of the IC population, became recognized as a significant cause of morbidity and mortality. Due to improved intensive care medicine (including adequate early resuscitation, analgesia, sedation) the incidence of stress ulcer-related bleeding in the IC has decreased markedly. Without pharmacological prophylaxis incidences ranging from 0.6 to 6% were reported. It is not recommended to apply stress ulcer prophylaxis on a routine basis, it should be reserved for patients with an increased risk of a stress ulcer-related bleeding. In patients with neurotrauma, severe burn, recent peptic ulcer or bleeding and those with coagulopathy prophylaxis with ranitidine is advised.

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