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Strategieën om de outcome in obstetrische anesthesie en analgesie te verbeteren / Towards strategies to improve outcome of obstetric anaesthesia and analgesia

Authors
  • Roofthooft, Eva Dirk Rita; 129864;
Publication Date
Feb 20, 2024
Source
Lirias
Language
English
License
Unknown
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Abstract

Annually, millions of women give birth worldwide. Birthing often requires anaesthetic support, either to relieve pain (by giving analgesia during labour for vaginal delivery) or to perform anaesthesia for Caesarean section (CS). Additionally, obstetric anaesthetists play a crucial role in co-managing obstetric complications such as preeclampsia and obstetric haemorrhage. Therefore, obstetric anaesthesia and analgesia plays a crucial role in the safe management of pregnant patients. Despite significant advancements in labour analgesia and anaesthesia for CS, several problems remain. The overall aim of this PhD project is to improve obstetric analgesia and anaesthesia. To achieve this aim, this PhD project contains two work packages (WP): WP 1: Evaluation of the quality of neuraxial labour analgesia and design and testing of strategies to optimize neuraxial analgesia using PIEB or PCEA for analgesia maintenance. We want to assess effects of no background infusion and different bolus volumes on labour outcome. WP 2: Assessment and optimization of the quality of neuraxial anaesthesia for CS and analgesia after CS. First, we want to determine the incidence of intraoperative breakthrough pain and possible risk factors in daily clinical practice. Secondly we want to produce recommendations on optimal strategies for analgesia after CS based on prospectively gathered, high-quality evidence, test them in clinical daily practice and investigate the effect of high-dose dexamethasone. / status: published

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