Stimulation of the hypothalamic-pituitary-adrenal axis with the opioid antagonist nalmefene.
- Published Article
- Publication Date
Jan 01, 2005
Of the nalmefene doses we studied, 6 mg achieved the best combination of stimulation of ACTH and cortisol and fewest side effects. If further studies show a concordance between nalmefene and IHT, nalmefene testing could be used to assess the HPA axis in patients at risk for dysfunction of this axis.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/16379031