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The stiffening of arteries by the tissue-mimicking gelatin.

Authors
Type
Published Article
Journal
IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control
0885-3010
Publisher
Institute of Electrical and Electronics Engineers
Publication Date
Volume
53
Issue
8
Pages
1534–1539
Identifiers
PMID: 16921906
Source
Medline
License
Unknown

Abstract

Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. PWV is measured by the time of travel of the "foot" of the pressure wave over a known distance. This technique has a low time resolution and is an average measurement of artery stiffness between the two measuring sites. The elastic modulus of the artery can be estimated with PWV, but the surrounding tissue effects are not considered. In this paper an external short pulse wave is generated noninvasively in the arterial wall by the radiation force of ultrasound. The pulse wave velocity in the artery is measured by a scanning technique with high-time resolution. The effect of tissue-mimicking gelatin on the artery is analyzed by measuring the wave velocity of the artery without and embedded in gelatin. It is found that the tissue-mimicking gelatin significantly stiffens the rubber tube and the artery if they are embedded in gelatin.

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