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Stiff person syndrome does not always occur with maternal passive transfer of GAD65 antibodies.

Authors
  • Nemni, R
  • Caniatti, L M
  • Gironi, M
  • Bazzigaluppi, E
  • De Grandis, D
Type
Published Article
Journal
Neurology
Publisher
Ovid Technologies (Wolters Kluwer) - American Academy of Neurology
Publication Date
Jun 08, 2004
Volume
62
Issue
11
Pages
2101–2102
Identifiers
PMID: 15184624
Source
Medline
License
Unknown

Abstract

The authors report the presence of high titer antibodies to glutamic acid decarboxylase (anti-GAD65) until age 24 months in two asymptomatic newborns of a woman with stiff-person syndrome (SPS). No signs of SPS were detectable in the two children at ages 6 and 8 years. This observation indicates that other cofactors are involved in the pathogenesis of SPS.

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