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A step towards the discrimination of beta-lactamase-producing clinical isolates of Enterobacteriaceae and Pseudomonas aeruginosa by MALDI-TOF mass spectrometry.

Authors
  • Schaumann, Reiner
  • Knoop, Nicolas
  • Genzel, Gelimer H
  • Losensky, Kevin
  • Rosenkranz, Christiane
  • Stîngu, Catalina S
  • Schellenberger, Wolfgang
  • Rodloff, Arne C
  • Eschrich, Klaus
Type
Published Article
Journal
Medical Science Monitor
Publisher
"International Scientific Information, Inc."
Publication Date
August 2012
Volume
18
Issue
9
Identifiers
PMID: 22936198
Source
Medline
License
Unknown

Abstract

This shows that MALDI-TOF MS has definite potential to discriminate antibiotic-resistant strains due to ESBL and MBL production from nonproducing strains, but this performance is not yet sufficiently reliable for routine microbiological diagnostics.

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