A step towards the discrimination of beta-lactamase-producing clinical isolates of Enterobacteriaceae and Pseudomonas aeruginosa by MALDI-TOF mass spectrometry.

Reiner Schaumann; Nicolas Knoop; Gelimer H Genzel; Kevin Losensky; Christiane Rosenkranz; Catalina S Stîngu; Wolfgang Schellenberger; Arne C Rodloff; Klaus Eschrich

A step towards the discrimination of beta-lactamase-producing clinical isolates of Enterobacteriaceae and Pseudomonas aeruginosa by MALDI-TOF mass spectrometry.

Authors

Schaumann, Reiner
Knoop, Nicolas
Genzel, Gelimer H
Losensky, Kevin
Rosenkranz, Christiane
Stîngu, Catalina S
Schellenberger, Wolfgang
Rodloff, Arne C
Eschrich, Klaus

Type

Published Article

Journal

Medical Science Monitor

Publisher

"International Scientific Information, Inc."

Publication Date

August 2012

Volume

18

Issue

9

Identifiers

PMID: 22936198

Source

Medline

License

Unknown

Abstract

This shows that MALDI-TOF MS has definite potential to discriminate antibiotic-resistant strains due to ESBL and MBL production from nonproducing strains, but this performance is not yet sufficiently reliable for routine microbiological diagnostics.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 07/04/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/22936198

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