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Step-down approach using either cyclosporin A or methotrexate as maintenance therapy in early rheumatoid arthritis.

Authors
  • Marchesoni, Antonio
  • Battafarano, Norma
  • Arreghini, Marco
  • Pellerito, Raffaele
  • Cagnoli, Maria
  • Prudente, Porziana
  • Cerase, Alfonso
  • Priolo, Francesco
  • Tosi, Sergio
Type
Published Article
Journal
Arthritis and rheumatism
Publication Date
Feb 01, 2002
Volume
47
Issue
1
Pages
59–66
Identifiers
PMID: 11932879
Source
Medline
License
Unknown

Abstract

Stepping down to single agent maintenance therapy following 6 months of combination treatment with CSA and MTX in early RA was only successful with MTX. Because this treatment did not prevent some radiographic progression, other approaches (e.g., step-up approach) may be more appropriate in early RA.

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