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Stem cell therapy: a future treatment of stress urinary incontinence.

Authors
Type
Published Article
Journal
Seminars in reproductive medicine
Publication Date
Volume
29
Issue
1
Pages
61–70
Identifiers
DOI: 10.1055/s-0030-1268705
PMID: 21207335
Source
Medline
License
Unknown

Abstract

The main urinary continence mechanism in human is the striated muscle rhabdosphincter that forms a ring around the mid-urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence (SUI) may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells.

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