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Steady-state pharmacokinetic, safety, and tolerability profiles of quetiapine, norquetiapine, and other quetiapine metabolites in pediatric and adult patients with psychotic disorders.

Authors
  • Winter, Helen R
  • Earley, Willie R
  • Hamer-Maansson, Jennifer E
  • Davis, Patty C
  • Smith, Mark A
Type
Published Article
Journal
Journal of child and adolescent psychopharmacology
Publication Date
Feb 01, 2008
Volume
18
Issue
1
Pages
81–98
Identifiers
DOI: 10.1089/cap.2007.0084
PMID: 18294091
Source
Medline
License
Unknown

Abstract

Pediatric and adult populations demonstrated similar pharmacokinetic, safety, and tolerability profiles for quetiapine administered by dose escalation. The predictability in quetiapine concentration profiles for children aged 10 years to adults suggests that no dosage adjustment may be required when treating patients of these ages.

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