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Steady state enzyme kinetics for systems with three enzyme-binding species.

Authors
  • Czerlinski, G H
Type
Published Article
Journal
Physiological chemistry and physics and medical NMR
Publication Date
Jan 01, 1986
Volume
18
Issue
3
Pages
189–196
Identifiers
PMID: 3588696
Source
Medline
License
Unknown

Abstract

The steady state enzyme kinetics of those systems are discussed, which involve three species binding to enzymes. Two specific systems are considered. In one system, all three species bind only once to the enzyme. In the other system, two species bind once and one binds twice to the enzyme. The species are labeled S, A and B. The general case is considered, in which all possible complexes involving enzyme E and species S generate product P. Species A and B may become co-substrates, activators or inhibitors. The steady state enzyme kinetic equations for the general case for both systems are presented. These equations are further discussed for a number of special cases, which may be of interest to enzymologists and others using enzymes.

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