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Steady-state bioavailability of extended-release methylphenidate (MPH-MLR) capsule vs. immediate-release methylphenidate tablets in healthy adult volunteers.

Authors
  • Adjei, Akwete
  • Kupper, Robert J
  • Teuscher, Nathan S
  • Wigal, Sharon
  • Sallee, Floyd
  • Childress, Ann
  • Kollins, Scott H
  • Greenhill, Laurence
Type
Published Article
Journal
Clinical Drug Investigation
Publisher
Springer-Verlag
Publication Date
Nov 01, 2014
Volume
34
Issue
11
Pages
795–805
Identifiers
DOI: 10.1007/s40261-014-0234-x
PMID: 25274428
Source
Medline
License
Unknown

Abstract

MPH-MLR 80-mg capsule once daily or IR methylphenidate 25 mg three times daily provides comparable maximum methylphenidate concentrations and systemic exposure in the fed state.

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