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A Staphylococcus xylosus isolate with a new mecC allotype.

Authors
  • Harrison, Ewan M1
  • Paterson, Gavin K
  • Holden, Matthew T G
  • Morgan, Fiona J E
  • Larsen, Anders Rhod
  • Petersen, Andreas
  • Leroy, Sabine
  • De Vliegher, Sarne
  • Perreten, Vincent
  • Fox, Lawrence K
  • Lam, Theo J G M
  • Sampimon, Otlis C
  • Zadoks, Ruth N
  • Peacock, Sharon J
  • Parkhill, Julian
  • Holmes, Mark A
  • 1 University of Cambridge, Department of Veterinary Medicine, Cambridge, United Kingdom. , (United Kingdom)
Type
Published Article
Journal
Antimicrobial Agents and Chemotherapy
Publisher
American Society for Microbiology
Publication Date
Mar 01, 2013
Volume
57
Issue
3
Pages
1524–1528
Identifiers
DOI: 10.1128/AAC.01882-12
PMID: 23274660
Source
Medline
Language
English
License
Unknown

Abstract

Recently, a novel variant of mecA known as mecC (mecA(LGA251)) was identified in Staphylococcus aureus isolates from both humans and animals. In this study, we identified a Staphylococcus xylosus isolate that harbors a new allotype of the mecC gene, mecC1. Whole-genome sequencing revealed that mecC1 forms part of a class E mec complex (mecI-mecR1-mecC1-blaZ) located at the orfX locus as part of a likely staphylococcal cassette chromosome mec element (SCCmec) remnant, which also contains a number of other genes present on the type XI SCCmec.

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