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Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Authors
  • Fiedler, Georg Martin1
  • Baumann, Sven
  • Leichtle, Alexander
  • Oltmann, Anke
  • Kase, Julia
  • Thiery, Joachim
  • Ceglarek, Uta
  • 1 Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital, Leipzig, Germany. , (Germany)
Type
Published Article
Journal
Clinical chemistry
Publication Date
Mar 01, 2007
Volume
53
Issue
3
Pages
421–428
Identifiers
PMID: 17272489
Source
Medline
License
Unknown

Abstract

This reliable pretreatment protocol allows standardization of preanalytical modalities and facilitates reproducible peptidome profiling of human urine by means of MB separation in combination with MALDI-TOF MS.

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