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Standardization of assay representation in the Ontology for Biomedical Investigations.

Authors
  • Vita, Randi1
  • Zheng, Jie2
  • Jackson, Rebecca1, 3
  • Dooley, Damion4
  • Overton, James A1, 3
  • Miller, Mark A5
  • Berrios, Daniel C6
  • Scheuermann, Richard H1, 7, 8
  • He, Yongqun9
  • McGinty, Hande Küçük10
  • Brochhausen, Mathias11
  • Lin, Aisyah Yu12
  • Jain, Sagar B7
  • Chibucos, Marcus C13
  • Judkins, John14
  • Giglio, Michelle G13
  • Feng, Irene Y15
  • Burns, Gully16
  • Brush, Matthew H17
  • Peters, Bjoern1, 18
  • And 1 more
Type
Published Article
Journal
Database
Publisher
Oxford University Press
Publication Date
Jul 08, 2021
Volume
2021
Identifiers
DOI: 10.1093/database/baab040
PMID: 34244718
Source
Medline
Language
English
License
Unknown

Abstract

The Ontology for Biomedical Investigations (OBI) underwent a focused review of assay term annotations, logic and hierarchy with a goal to improve and standardize these terms. As a result, inconsistencies in W3C Web Ontology Language (OWL) expressions were identified and corrected, and additionally, standardized design patterns and a formalized template to maintain them were developed. We describe here this informative and productive process to describe the specific benefits and obstacles for OBI and the universal lessons for similar projects. © The Author(s) 2021. Published by Oxford University Press.

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