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Staging for cutaneous squamous cell carcinoma as a predictor of sentinel lymph node biopsy results: meta-analysis of American Joint Committee on Cancer criteria and a proposed alternative system.

Authors
  • Schmitt, Adam R
  • Brewer, Jerry D
  • Bordeaux, Jeremy S
  • Baum, Christian L
Type
Published Article
Journal
JAMA dermatology
Publication Date
Jan 01, 2014
Volume
150
Issue
1
Pages
19–24
Identifiers
DOI: 10.1001/jamadermatol.2013.6675
PMID: 24226651
Source
Medline
License
Unknown

Abstract

Our findings suggest that most cSCCs associated with positive SLNB findings occur in T2 lesions (in both staging systems) that are greater than 2 cm in diameter. The alternative staging system appears to more precisely delineate high-risk lesions in the T2b category that may warrant consideration of SLNB. Future prospective studies are necessary to validate the relationship between tumor stage and positive SLNB findings and to identify the optimal staging system.

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