Affordable Access

deepdyve-link
Publisher Website

Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis.

Authors
  • Hsu, Chiung-Yueh1
  • Lecland, Nicolas1
  • Pendaries, Valérie2
  • Viodé, Cécile3
  • Redoulès, Daniel3
  • Paul, Carle4
  • Merdes, Andreas5
  • Simon, Michel6
  • Bierkamp, Christiane7
  • 1 Centre de Biologie du Développement, Université Paul Sabatier/CNRS, 31062, Toulouse, France. , (France)
  • 2 INSERM-Université Paul Sabatier U1056, UDEAR, CHU Purpan, 31059, Toulouse, France. , (France)
  • 3 Pierre Fabre Dermo-Cosmétique, 3 Avenue Hubert Curien, 31100, Toulouse, France. , (France)
  • 4 INSERM-Université Paul Sabatier U1056, UDEAR, CHU Purpan, 31059, Toulouse, France; Dermatologie, Hôpital Larrey, Centre Hospitalier Universitaire de Toulouse, 31059, Toulouse, France. , (France)
  • 5 Centre de Biologie du Développement, Université Paul Sabatier/CNRS, 31062, Toulouse, France. Electronic address: [email protected] , (France)
  • 6 INSERM-Université Paul Sabatier U1056, UDEAR, CHU Purpan, 31059, Toulouse, France. Electronic address: [email protected] , (France)
  • 7 Centre de Biologie du Développement, Université Paul Sabatier/CNRS, 31062, Toulouse, France. Electronic address: [email protected] , (France)
Type
Published Article
Journal
Journal of dermatological science
Publication Date
Apr 18, 2018
Identifiers
DOI: 10.1016/j.jdermsci.2018.04.008
PMID: 29691121
Source
Medline
Keywords
License
Unknown

Abstract

Our data suggest that the microtubule network is important for the formation of the epidermis, and that stabilization of microtubules promotes barrier formation. Microtubule stabilization may support regeneration of damaged skin, by restoring or improving the barrier.

Report this publication

Statistics

Seen <100 times