Affordable Access

deepdyve-link
Publisher Website

Stability of Sensory Topographies in Adult Cortex.

Authors
  • Makin, Tamar R1
  • Bensmaia, Sliman J2
  • 1 FMRIB Centre, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford OX39DU, UK; Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, UK. Electronic address: [email protected]
  • 2 Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL, USA.
Type
Published Article
Journal
Trends in cognitive sciences
Publication Date
Mar 01, 2017
Volume
21
Issue
3
Pages
195–204
Identifiers
DOI: 10.1016/j.tics.2017.01.002
PMID: 28214130
Source
Medline
License
Unknown

Abstract

Textbooks teach us that the removal of sensory input to sensory cortex, for example, following arm amputation, results in massive reorganisation in the adult brain. In this opinion article, we critically examine evidence for functional reorganisation of sensory cortical representations, focusing on the sequelae of arm amputation on somatosensory topographies. Based on literature from human and non-human primates, we conclude that the cortical representation of the limb remains remarkably stable despite the loss of its main peripheral input. Furthermore, the purportedly massive reorganisation results primarily from the formation or potentiation of new pathways in subcortical structures and does not produce novel functional sensory representations. We discuss the implications of the stability of sensory representations on the development of upper-limb neuroprostheses.

Report this publication

Statistics

Seen <100 times