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The SRD5A2 V89L polymorphism is associated with severity of disease in men with early onset prostate cancer.

Authors
  • Scariano, John K
  • Treat, Eric
  • Alba, Frances
  • Nelson, Harold
  • Ness, Scott A
  • Smith, Anthony Y
Type
Published Article
Journal
The Prostate
Publisher
Wiley (John Wiley & Sons)
Publication Date
Dec 01, 2008
Volume
68
Issue
16
Pages
1798–1805
Identifiers
DOI: 10.1002/pros.20842
PMID: 18780294
Source
Medline
License
Unknown

Abstract

The SRD5A2 leucine isoform appears to be acting in a dose-dependent manner as a significant disease-modifying factor in young men diagnosed with PCa.

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