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Squamous cell carcinoma in the setting of chronic hidradenitis suppurativa; report of a patient and update of the literature.

Authors
Type
Published Article
Journal
Dermatology online journal
Volume
21
Issue
4
Source
Sivamani Lab - UC Davis dermatology-ucdavis
License
Unknown

Abstract

Squamous cell carcinoma (SCC) developing in chronic hidradenitis suppurativa (HS) is rare, but failing to recognize the condition may have significant consequences. Dermatologists must be aware of the potential for malignant transformation and should have a low threshold for biopsy when clinical presentation is atypical. Herein we describe a 64-year-old woman with metastatic vulvar SCC that developed within an area of chronic HS. Like SCC associated with other chronic inflammatory disorders (Marjolin s ulcers), mortality is significant. Past reviews have reported death rates above 40% and our most recent update continues to support poor prognoses for these patients.

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