Sputum neutrophilia can mask eosinophilic bronchitis during exacerbations.
Firestone Institute for Respiratory Health, St. Joseph's Healthcare, and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
- Published Article
Canadian respiratory journal
- Publication Date
Jan 01, 2007
A neutrophilic exacerbation of airway disease was observed to mask sputum eosinophilia in one-third of patients who had sputum cell counts available before and after antibiotic therapy. Hence, the absence of sputum eosinophilia during an infective exacerbation should not be used as an indication to reduce the dose of corticosteroids. To optimize therapy, repeat sputum cell count measurements are recommended after antibiotic treatment before changing corticosteroid treatment.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/17703243