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Sputum ADAM8 expression is increased in severe asthma and COPD.

Authors
  • Oreo, K M
  • Gibson, P G
  • Simpson, J L
  • Wood, L G
  • McDonald, V M
  • Baines, K J
Type
Published Article
Journal
Clinical & Experimental Allergy
Publisher
Wiley (Blackwell Publishing)
Publication Date
Mar 01, 2014
Volume
44
Issue
3
Pages
342–352
Identifiers
DOI: 10.1111/cea.12223
PMID: 24147597
Source
Medline
License
Unknown

Abstract

ADAM8 expression is increased in both severe asthma and COPD and associated with sputum total cell count and neutrophils. ADAM8 may facilitate neutrophil migration to the airways in severe asthma and COPD.

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