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The SPOTS System: An Ocular Scoring System Optimized for Use in Modern Preclinical Drug Development and Toxicology.

Authors
  • Eaton, Joshua Seth1, 2
  • Miller, Paul E1, 3
  • Bentley, Ellison1, 3
  • Thomasy, Sara M1, 2
  • Murphy, Christopher J1, 2, 4
  • 1 1 Ocular Services On Demand (OSOD) , LLC, Madison, Wisconsin.
  • 2 2 Department of Surgical & Radiological Sciences, School of Veterinary Medicine, University of California-Davis , Davis, California.
  • 3 3 Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison , Madison, Wisconsin.
  • 4 4 Department of Ophthalmology & Vision Science, School of Medicine, University of California-Davis , Sacramento, California.
Type
Published Article
Journal
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Publication Date
Dec 01, 2017
Volume
33
Issue
10
Pages
718–734
Identifiers
DOI: 10.1089/jop.2017.0108
PMID: 29239680
Source
Medline
Keywords
License
Unknown

Abstract

The SPOTS systems provide criteria that stand to enhance the applicability of semiquantitative scoring criteria to the full range of laboratory species, in the context of modern approaches to ocular therapeutics and drug delivery and drug and device development.

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