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Spontaneous lesions of the mouse biliary tract.

Authors
Type
Published Article
Journal
Journal of comparative pathology
Publication Date
Volume
94
Issue
2
Pages
263–271
Identifiers
PMID: 6736312
Source
Medline

Abstract

During the routine histological examination of 2400 aged mice from lifespan carcinogenicity studies a low prevalence of glandular metaplasia of the gall bladder and of the intra-hepatic bile ducts (all associated with cholelithiasis), cholecystitis, cholangitis, papillomatous hyperplasia, papilloma, intra-mural cysts, and focal epithelial ulceration was found. The lesions were found predominantly in female mice and were not treatment related.

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