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Spirostanol pentaglycosides from the underground parts of polianthestuberosa.

Authors
  • Mimaki, Yoshihiro
  • Yokosuka, Akihito
  • Sakuma, Chiseko
  • Sakagami, Hiroshi
  • Sashida, Yutaka
Type
Published Article
Journal
Journal of natural products
Publication Date
Oct 01, 2002
Volume
65
Issue
10
Pages
1424–1428
Identifiers
PMID: 12398537
Source
Medline
License
Unknown

Abstract

Phytochemical analysis of the underground parts of Polianthes tuberosa has resulted in the isolation of four new spirostanol saponins with five monosaccharides (1-4). Their structures were determined by spectroscopic analysis, including extensive 1D and 2D NMR data, and the results of hydrolytic cleavage. The cytotoxic activities of 1-4 against HL-60 human promyelocytic leukemia cells and HSC-2 human oral squamous cell carcinoma cells are reported.

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