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Spinal cord atrophy in spinocerebellar ataxia type 3 and 6 : impact on clinical disability.

Authors
  • Lukas, Carsten1
  • Hahn, Horst K
  • Bellenberg, Barbara
  • Hellwig, Kerstin
  • Globas, Christoph
  • Schimrigk, Sebastian K
  • Köster, Odo
  • Schöls, Ludger
  • 1 Dept. of Diagnostic and Interventional Radiology and Nuclear Medicine, St. Josef Hospital Ruhr University Bochum, Gudrunstr. 56, 44791, Bochum, Germany. [email protected]
Type
Published Article
Journal
Journal of neurology
Publication Date
August 2008
Volume
255
Issue
8
Pages
1244–1249
Identifiers
DOI: 10.1007/s00415-008-0907-6
PMID: 18506570
Source
Medline
License
Unknown

Abstract

Our results quantify for the first time in vivo spinal cord atrophy as a non-cerebellar neurodegenerative process in SCA3. Our results suggest MR volumetry of the upper cervical cord as a marker of functional importance in SCA3 and SCA6.

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