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The spectrum of antiviral activities of acyclovir in vitro and in vivo.

Authors
  • Collins, P
Type
Published Article
Journal
The Journal of antimicrobial chemotherapy
Publication Date
Sep 01, 1983
Volume
12 Suppl B
Pages
19–27
Identifiers
PMID: 6313598
Source
Medline
License
Unknown

Abstract

In vitro sensitivity data suggest that acyclovir should be effective against clinical manifestations of herpes simplex virus types 1 and 2, varicella-zoster virus and possibly Epstein-Barr virus. The clinical potential against herpes simplex virus types 1 and 2 is further supported by results in animal models. Human cytomegalovirus and the veterinary herpes viruses, with the possible exception of equine herpes virus type 1, may be insufficiently sensitive to be amenable to treatment.

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