Affordable Access

Access to the full text

Spectroscopic and Imaging Characteristics of Pigmented Non-Melanoma Skin Cancer and Melanoma in Patients with Skin Phototypes III and IV

  • Arroyo-Camarena, Stefanie1
  • Domínguez-Cherit, Judith2
  • Lammoglia-Ordiales, Lorena1
  • Fabila-Bustos, Diego A.3, 4
  • Escobar-Pio, Abraham3
  • Stolik, Suren3
  • Valor-Reed, Alma3
  • de la Rosa-Vázquez, José3
  • 1 Hospital General “Dr. Manuel Gea González”, División de Dermatología, Ciudad de México, 14080, México , Ciudad de México (Mexico)
  • 2 Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Departamento de Dermatología, Ciudad de México, 14080, México , Ciudad de México (Mexico)
  • 3 ESIME Zac, Instituto Politécnico Nacional, Laboratorio de Biofotónica, Ciudad de México, 07738, México , Ciudad de México (Mexico)
  • 4 UPIIH, Instituto Politécnico Nacional, Ciudad del Conocimiento y la Cultura, Departamento de Formación Básica Disciplinaria, Pachuca de Soto, Hidalgo, 42162, México , Pachuca de Soto (Mexico)
Published Article
Oncology and Therapy
Springer Healthcare
Publication Date
Dec 12, 2016
DOI: 10.1007/s40487-016-0036-9
Springer Nature


IntroductionNon-melanoma skin cancer is the most common malignancy worldwide. Differentiating between malignant and benign skin tumors, however, can be challenging. As a result, various auxiliary tools have been developed to aid in the diagnosis of cutaneous neoplasms. Here, skin tumors were investigated through analysis of their digital image histograms and spectroscopic response under ultraviolet (UV) and white light-emitting diodes (LEDs).MethodsFifty tumoral lesions were spectroscopically and histologically studied. For optical studies, UV at 375 nm and white LEDs were used to illuminate the lesions. Commercial cameras were used for imaging, and a miniature spectrometer with a bifurcated optical fiber was used for spectroscopic measurements.ResultsIn this study, the intensity histograms of the images taken under white and UV illumination and the spectroscopic response under white light showed clear differences between pigmented basal cell carcinoma (BCC), intradermal melanocytic nevus (IDN), and melanoma lesions for skin phototypes III and IV. However, there was little difference in their spectroscopic response to the UV LED.ConclusionWe found differences in the intensity and shape of diffuse reflectance spectra of pigmented BCC, IDN, and melanoma lesions in patients with skin phototypes III and IV. Also, images taken under UV and white light were helpful for differentiation of these pigmented lesions. Additional research is needed to ascertain the clinical utility of these tools for skin cancer diagnosis.

Report this publication


Seen <100 times