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The spectrophotometric determination of streptomycins.

Authors
  • Wahbi, A M
  • Abdine, H
  • Rafik, A
  • Sadek, H
Type
Published Article
Journal
Die Pharmazie
Publication Date
Nov 01, 1977
Volume
32
Issue
11
Pages
690–692
Identifiers
PMID: 76315
Source
Medline
License
Unknown

Abstract

The spectra produced by the acid treatment and alkaline treatment of streptomycin and dihydrostreptomycin have been investigated to obtain suitable methods for their determination. Mixtures of the two antibiotics have been successfully determined in the UV region. Thus, using the orthogonal function method, dihydrostreptomycin has been determined after acid treatment whereas streptomycin has been determined after alkaline treatment followed by immediate neutralization.

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