Affordable Access

Specificity of oxygen radical scavengers and assessment of free radical scavenger efficiency using luminol enhanced chemiluminescence.

Authors
  • Rao, P S1
  • Luber, J M Jr
  • Milinowicz, J
  • Lalezari, P
  • Mueller, H S
  • 1 Division of Cardiothoracic Surgery, Long Island Jewish Medical Center, New Hyde Park, NY 11042.
Type
Published Article
Journal
Biochemical and biophysical research communications
Publication Date
Jan 15, 1988
Volume
150
Issue
1
Pages
39–44
Identifiers
PMID: 2827676
Source
Medline
License
Unknown

Abstract

The selective scavenging capacities of 19 important oxygen radical scavengers were determined by adding them individually to each of the four oxy radical standards, (superoxide, hydroxy, alkoxy and hydroperoxy, and singlet O2), calculating the percent chemiluminescence inhibited, and extrapolating O2 equivalents neutralized from baseline. The sensitivity (0.01 nm/ml) and selectivity of this method not only allows identification of individual oxygen free radical species but also quantitates the efficiency of free radical scavengers.

Report this publication

Statistics

Seen <100 times