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Specificity may be overrated in cancer immunotherapy: Getting to know the nonspecific side of memory T Cells.

Authors
Type
Published Article
Journal
OncoImmunology
Publisher
Landes Bioscience
Volume
1
Issue
7
Pages
1208–1208
Source
Murphy Lab dermatology-ucdavis
License
Unknown

Abstract

For a long time, cancer immunotherapy has focused on the induction of tumor-specific T cell-mediated immune responses. Now, a mounting body of evidence indicates that efficient anticancer immune responses also rely on innate immunity. Tietze et al. have recently elucidated an antigen-nonspecific role for memory CD8(+) T cells in cytokine-based cancer immunotherapy.

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