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Specific forms of BAFF favor BAFF receptor-mediated epithelial cell survival

Authors
  • Lahiri, Ayan
  • Varin, Marie-Michèle
  • Le Pottier, Laëtitia
  • Pochard, Pierre
  • Bendaoud, Boutahar
  • Youinou, Pierre
  • Pers, Jacques-Olivier1, 2, 3, 4
  • 1 EA2216 “Immunology and Pathology”
  • 2 LabEx IGO
  • 3 SFR ScInBioS
  • 4 European University of Brittany and Brest University
Type
Published Article
Journal
Journal of Autoimmunity
Publisher
Elsevier BV
Publication Date
Jan 01, 2014
Accepted Date
Feb 05, 2014
Identifiers
DOI: 10.1016/j.jaut.2014.02.004
Source
Elsevier
Keywords
License
Unknown

Abstract

•Epithelial cells express BAFF-receptor and produce BAFF.•Blocking BAFF-receptor in epithelial cells promotes apoptosis.•Only some forms of BAFF are required for epithelial cell survival.

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