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A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA.

Authors
Type
Published Article
Journal
The American journal of tropical medicine and hygiene
Publication Date
Volume
40
Issue
4
Pages
377–383
Identifiers
PMID: 2712196
Source
Medline

Abstract

An echinococcus antigen with an apparent molecular weight of 8 kDa was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. Specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.

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