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Specialization of tumour vasculature.

Authors
Type
Published Article
Journal
Nat Rev Cancer
Volume
2
Issue
2
Pages
83–90
Source
Ruoslahti Lab
License
Unknown

Abstract

Tumour blood vessels express markers that are not present in resting blood vessels of normal tissues, but that can be shared by angiogenic vessels in non-malignant conditions. Many of these proteins are functionally important in the angiogenic process. Some tumours also contain lymphatic vessels, as well as channels that consist of cancer cells and their extracellular matrix. These special features of tumour vessels are good targets for cancer therapies.

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