Affordable Access

Spatial learning and motor deficits in aged rats.

Authors
  • Gage, F H
  • Dunnett, S B
  • Björklund, A
Type
Published Article
Journal
Neurobiology of Aging
Publisher
Elsevier
Publication Date
Jan 01, 1984
Volume
5
Issue
1
Pages
43–48
Identifiers
PMID: 6738785
Source
Medline
License
Unknown

Abstract

Young (3 months) and aged (24 months) rats were compared on a range of behavioural tests. The aged animals were impaired in their acquisition of a spatial learning task in the Morris water maze, as well as showing deficits in motor coordination, swimming efficiency, and spontaneous locomotion and exploration in an open field. Qualitative observation and correlation analyses indicated that the aged group was heterogeneous in the degree of impairments manifested by the individual animals, and suggested that the development of impairments may progress with aging at different rates in the various tasks and possibly in different underlying neuroanatomical systems.

Report this publication

Statistics

Seen <100 times