Sonication, calcium, and peptides have systematic effects on the nonlinear dynamics of tyrosine hydroxylase activity.
- Published Article
- Publication Date
Jan 01, 1986
Sonication, dialysis, calcium, and peptides have systematic effects on the nonlinear dynamics of tyrosine hydroxylase (TOH). Under standard assay conditions TOH shows a high amplitude fluctuation in catalytic output across time that is eliminated either by sonication or by dialysis. This coherent dynamic is restored with the addition to the dialyzed preparation of either calcium in micromolar concentrations or certain peptides (SOM, MSH), but not others (CCK, TRH).
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/20493114