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Some methodological problems in age comparisons of EEG sleep patterns for C57BL/6J mice.

Authors
  • Elias, M F
  • Elias, P K
  • Zolovick, A J
  • Eleftheriou, B E
Type
Published Article
Journal
Experimental aging research
Publication Date
Sep 01, 1975
Volume
1
Issue
1
Pages
107–119
Identifiers
PMID: 1053197
Source
Medline
License
Unknown

Abstract

Some methodological problems encountered in age comparisons of EEG patterns are discussed in the context of an analysis of open field activity scores before and after preparation for, and recording of EEG sleep patterns. Plasma corticosterone levels 11 days after surgery for EEG electrode implantation were also measured. Activity levels were modified more for three older than for a younger group of animals following surgery/recording sessions. Corticosterone levels were appreciably elevated for the oldest group of animals. The possibility was raised that procedures designed to allow recovery from post surgical shock and adaptation to electrode connections may result in disproportionate differences across age groups.

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