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Somatosensory evoked potentials in Huntington's disease--studies with paired stimulation.

Authors
  • Kanda, F
  • Jinnai, K
  • Takahashi, K
  • Abe, H
  • Yasuda, M
  • Tada, K
  • Fujita, T
Type
Published Article
Journal
Electromyography and clinical neurophysiology
Publication Date
Jan 01, 1989
Volume
29
Issue
5
Pages
287–291
Identifiers
PMID: 2527738
Source
Medline
License
Unknown

Abstract

The somatosensory evoked potentials (SEPs) and recovery functions of the SEP with paired stimulation were studied in patients with Huntington's disease (HD). A significant decrease in amplitude of the SEP was observed in 4 of the 5 patients. In addition, with paired stimulation, the second SEP amplitudes were normalized at intervals of about 10 ms. These findings possibly suggest that functional block rather than organic change in the thalamus may play an important role in the reduction in SEP amplitude in HD.

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