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Solitary, multifocal and generalized myofibromas: clinicopathological and immunohistochemical features of 114 cases.

Authors
  • 1
  • 1 Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands. , (Netherlands)
Type
Published Article
Journal
Histopathology
1365-2559
Publication Date
Volume
60
Issue
6B
Identifiers
DOI: 10.1111/j.1365-2559.2012.04221.x
PMID: 22486319
Source
Medline
License
Unknown

Abstract

Solitary and multiple myofibromas are benign tumours that predominantly occur in infancy and childhood. Myofibromas occur especially in the head and neck region, and are characterized by SMA and, to a lesser extent, MSA expression. The clinical course is self-limiting, and local excision appears to be sufficient.

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